Drugs / MEDI5884
last change Oct 2021 re-read 3 minutes ago

MEDI5884

Monoclonal antibody

Developed for
coronary artery disorder
Investigated by
MedImmune LLC

Trials 2

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03001297 Jan 2017 → Aug 2018 — MedImmune LLC Completed No outcome recorded
Phase 21 trial
Phase 2 NCT03351738 Dec 2017 → Nov 2018 coronary artery disorder MedImmune LLC Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as MEDI5884 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03001297 ↗
1

NCT03351738 ↗

Action Inhibit “CONCLUSIONS: Inhibition of EL by MEDI5884 increases the quantity and quality of functional HDL in patients with stable coronary artery disease on high-intensity statin therapy...” PMID 34706556 ↗ Oct 2021
Modality Monoclonal antibody “MEDI5884 is a selective, humanized, monoclonal, EL-neutralizing antibody.” PMID 34706556 ↗ Oct 2021
Route Subcutaneous “single ascending subcutaneous doses of MEDI5884” NCT03001297 ↗