Drugs / Tebipenem
last change Dec 2025 re-read 2 minutes ago

Tebipenem

Small molecule

Developed for
bacterial urinary tract infection
Investigated by
Hartford Hospital · Spero Therapeutics

Trials 2 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05296382 Apr → Jun 2022 Hartford Hospital Completed No outcome recorded
Phase 1 NCT04919954 Jul 2021 → Aug 2022 bacterial infectious disease, diabetes mellitus, skin infection Hartford Hospital Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 4 NCT07236944 Comparator Dec 2025 → Mar 2029 expected bacterial urinary tract infection Uppsala University Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as tebipenem “and 4) tebipenem (if approved by the EMA).” NCT07236944
2

NCT04919954

NCT05296382

Known as SPR994 “This study will determine the tissue penetration of a broad-spectrum orally bioavailable carbapenem, tebipenem pivoxil hydrobromide (SPR994) (Spero Therapeutics, Inc.), into...” NCT04919954
1

“The purpose of this study is to measure the amount of the antibiotic, tebipenem (SPR994) that is bioavailable after crushing the tablet and administering through a feeding tube...” NCT05296382

Known as tebipenem pivoxil hydrobromide “This study will determine the tissue penetration of a broad-spectrum orally bioavailable carbapenem, tebipenem pivoxil hydrobromide (SPR994) (Spero Therapeutics, Inc.), into...” NCT04919954
Modality Small molecule “a broad-spectrum orally bioavailable carbapenem” NCT04919954
Route Oral “administered orally” NCT04919954