Drugs / NJH395
last change Dec 2022 re-read 3 minutes ago

NJH395

Monoclonal antibody targets TLR7 via activation

Developed for
carcinoma
Investigated by
Novartis Pharmaceuticals

Trials 1

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03696771 Dec 2018 → Oct 2020 carcinoma Novartis Pharmaceuticals Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as NJH395 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03696771 ↗
Action Activate “TLR7 agonism contributing to antitumor activity” PMID 36129967 ↗ Dec 2022
Modality Monoclonal antibody “consisting of a monoclonal antibody which targets HER2 conjugated to an immune-stimulatory agent” NCT03696771 ↗
Route Intravenous “Administered Intravenously” NCT03696771 ↗
Target TLR7 “a Toll-like receptor 7 (TLR7) agonist” PMID 36129967 ↗ Dec 2022