Drugs / Clesrovimab
last change Apr 2026 re-read 2 minutes ago

Clesrovimab

also known as MK-1654

Monoclonal antibody

Developed for
respiratory syncytial virus infectious disease
Investigated by
Merck Sharp & Dohme LLC

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved EU (EMA) Enflonsia 2026-04-15 europa.eu

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT03524118 Sep 2018 → Sep 2022 respiratory syncytial virus infectious disease Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04086472 Oct 2019 → Mar 2020 respiratory syncytial virus infectious disease Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT04767373 Apr 2021 → Jul 2024 respiratory syncytial virus infectious disease Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 31 trial
Phase 3 NCT04938830 Nov 2021 → Apr 2025 respiratory syncytial virus infectious disease Merck Sharp & Dohme LLC Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Clesrovimab ClinicalTrials.gov intervention name — accepted as the source's own label NCT04938830
3

NCT04767373

NCT03524118

NCT04086472

Known as MK-1654 MK-1654NCT04086472
Action Inhibit “Respiratory Syncytial Virus Neutralizing Antibody, Clesrovimab” PMID 39601265 Mar 2025
Modality Monoclonal antibody “Clesrovimab is an investigational monoclonal antibodyPMID 39601265 Mar 2025
Route Intramuscular “Single ascending doses of clesrovimab will be administered via IM injection.” NCT03524118