Drugs / TMB-365
last change Dec 2025 re-read 2 minutes ago

TMB-365

Monoclonal antibody targets CD4 via inhibition

Developed for
HIV infectious disease
Investigated by
TaiMed Biologics Inc. · Westat

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04027387 Dec 2019 → Aug 2021 HIV infectious disease TaiMed Biologics Inc. Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT05275998 Jul 2022 → Nov 2024 HIV infectious disease TaiMed Biologics Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT07215468 Dec 2025 → Aug 2027 expected HIV infectious disease TaiMed Biologics Inc. Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as TMB-365 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07215468
2

NCT05275998

NCT04027387

Action Inhibit “A monoclonal antibody acts as a HIV post-attachment inhibitor” NCT07215468
Modality Monoclonal antibody “An IgG1 monoclonal antibodyNCT04027387
Route Intravenous “administered via intravenous infusion (IV)” NCT04027387
Target CD4 “targeting domain 2 of the CD4 receptor” NCT04027387