Drugs / vatreptacog alfa (activated)
last change Sep 2012 re-read 2 minutes ago

vatreptacog alfa (activated)

Protein / enzyme biologic

Developed for
hemophilia A · hemophilia B
Investigated by
Novo Nordisk A/S

Trials 2 · a red edge is where a trial was stopped

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00822185 Jan → Jul 2009 hemorrhagic disease Novo Nordisk A/S Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00486278 Jun 2007 → Jun 2010 hemophilia A, hemophilia B Novo Nordisk A/S Completed No outcome recorded

Press releases naming this drug 2 releases

DateIssuerRelease
2012-09-28 Novo Nordisk A/S Novo Nordisk A/S: Novo Nordisk discontinues development of vatreptacog alfa following analysis of phase 3 results novonordisk.com
2012-09-28 Novo Nordisk A/S Novo Nordisk A/S: Novo Nordisk indstiller udviklingen af vatreptacog alfa efter analyse af fase 3-resultater novonordisk.com

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as vatreptacog alfa (activated) ClinicalTrials.gov intervention name — accepted as the source's own label NCT00486278
Known as NN1731 “A recombinant factor VIIa analog (NN1731; vatreptacog alfa [activated]) was developed to provide safe, rapid and sustained resolution of bleeds in patients with hemophilia and...” PMID 22470921 Jan 2012
1

“activated recombinant human coagulation factor VII analogue (NN1731, vatreptacog alfa (activated))” NCT00822185

Known as vatreptacog alfa ClinicalTrials.gov intervention name — accepted as the source's own label NCT00822185
Known as Vatreptacog alfa (activada) ChEMBL registry synonym — accepted as the source's own label CHEMBL2108322
Known as Vatreptacog alfa (active) ChEMBL registry synonym — accepted as the source's own label CHEMBL2108322
Modality Protein / enzyme biologic “A recombinant factor VIIa analog (NN1731; vatreptacog alfa [activated])” PMID 22470921 Jan 2012
Route Intravenous “5 mcg/kg, injected i.v.” NCT00486278