Drugs / BIIB091
last change Feb 2026 re-read 2 minutes ago

BIIB091

also known as [14C]-BIIB091

Small molecule targets BTK via inhibition

Developed for
multiple sclerosis
Investigated by
Biogen

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT06640933 Oct 2024 → Feb 2025 Biogen Completed No outcome recorded
Phase 1 NCT06574828 Aug 2024 → Mar 2025 Biogen Completed No outcome recorded
Phase 1 NCT06311786 Apr → May 2024 Biogen Completed No outcome recorded
Phase 1 NCT04564612 Sep 2020 → Sep 2022 Biogen Completed No outcome recorded
Phase 1 NCT03943056 May 2019 → Jan 2020 Biogen Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05798520 Jul 2023 → Feb 2026 multiple sclerosis Biogen Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as BIIB091 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05798520
5

NCT04564612

NCT06311786

NCT06574828

NCT03943056

NCT06640933

Known as [14C]-BIIB091 “Participants will receive a single oral dose of \[14C\]-BIIB091 on Day 1.” NCT06311786
Action Inhibit “BIIB091, a Bruton's Tyrosine Kinase (BTK) Inhibitor” NCT03943056
Modality Small molecule CHEMBL5083772
Route Oral “single and multiple oral doses of BIIB091” NCT03943056
Target BTK “BIIB091, a Bruton's Tyrosine Kinase (BTK) Inhibitor” NCT03943056