Drugs / Alkotinib
last change Oct 2022 re-read 3 minutes ago

Alkotinib

targets ALK, ROS1 via inhibition

Developed for
non-small cell lung carcinoma
Investigated by
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04032821 Nov → Dec 2019 non-small cell lung carcinoma Suzhou Zelgen Biopharmaceuticals Co.,Ltd Completed No outcome recorded
Phase 1 NCT03607188 Oct 2018 → Oct 2022 non-small cell lung carcinoma Suzhou Zelgen Biopharmaceuticals Co.,Ltd Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04211922 Jan 2020 → Oct 2022 non-small cell lung carcinoma Suzhou Zelgen Biopharmaceuticals Co.,Ltd Terminated No outcome recorded Stop: Business

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Alkotinib ClinicalTrials.gov intervention name — accepted as the source's own label NCT04211922 ↗
2

NCT04032821 ↗

NCT03607188 ↗

Action Inhibit “selectively inhibits anaplastic lymphoma Kinase and proto-oncogene protein ROS1” NCT04032821 ↗
Route Oral “ZG0418 200mg/day,oral” NCT03607188 ↗
Target ALK “Alkotinib is an insulin receptor tyrosine kinase inhibitor that selectively inhibits anaplastic lymphoma Kinase and proto-oncogene protein ROS1。Alkotinib is expected to be used...” NCT04032821 ↗
Target ROS1 “Alkotinib is an insulin receptor tyrosine kinase inhibitor that selectively inhibits anaplastic lymphoma Kinase and proto-oncogene protein ROS1。Alkotinib is expected to be used...” NCT04032821 ↗