drugset
Drugs / Allogeneic Pancreatic Islet Cells
last change Jul 2016 re-read 9 days ago

Allogeneic Pancreatic Islet Cells

also known as PHPI

Cell therapy

Developed for
type 1 diabetes mellitus
Investigated by
National Institute of Allergy and Infectious Diseases (NIAID) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Clinical Islet Transplantation Consortium

Trials 5

today NCT00468403 · Ph 2 NCT00468442 · Ph 2 NCT00434811 · Ph 3 NCT00434850 · Ph 2
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 23 trials
Phase 2 NCT00468403 Oct 2008 → Apr 2012 type 1 diabetes mellitus National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT00468442 Nov 2006 → Sep 2011 type 1 diabetes mellitus National Institute of Allergy and Infectious Diseases (NIAID) Terminated No outcome recorded
Phase 2 NCT00434850 Oct 2006 → Sep 2011 type 1 diabetes mellitus National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 31 trial · 1 met primary
Phase 3 NCT00434811 Oct 2006 → Sep 2012 type 1 diabetes mellitus National Institute of Allergy and Infectious Diseases (NIAID) Completed Met primary
Phase not stated1 trial
— NCT01049633 — type 1 diabetes mellitus National Institute of Allergy and Infectious Diseases (NIAID) No longer available No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT00790439 Background Jul 2008 → Oct 2009 type 1 diabetes mellitus National Institute of Allergy and Infectious Diseases (NIAID) Withdrawn No outcome recorded Stop: Business

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as Allogeneic Pancreatic Islet Cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT00434850 ↗
5

NCT01049633 ↗

NCT00790439 ↗

NCT00468403 ↗

NCT00434811 ↗

NCT00468442 ↗
Known as PHPI “purified human pancreatic islets (PHPI)” PMID 27208344 ↗ Apr 2016
Action Restore “Transplanted PHPI provided glycemic control, restoration of hypoglycemia awareness, and protection from SHEs” PMID 27208344 ↗ Apr 2016
Modality Cell therapy “a complex cellular product” PMID 27465220 ↗ Jul 2016
Route Other “infusion of islets into a branch of the portal vein” NCT00434811 ↗