Drugs / CC-3
last change May 2026 re-read 3 minutes ago

CC-3

targets CD276 via depletion

Developed for
breast carcinoma · colorectal cancer · penile carcinoma · sarcoma
Investigated by
German Cancer Research Center

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05999396 Jan 2024 → Oct 2026 expected breast carcinoma, colorectal cancer, penile carcinoma, sarcoma German Cancer Research Center Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as CC-3 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05999396 ↗
Action Deplete “CC-3 also induced potent tumor cell lysis and T cell proliferation across all patient-derived tumor samples” PMID 42094867 ↗ May 2026
Target CD276 “CC-3 binds to CD276 on cancer cells as well as to tumor vessels of CRC” NCT05999396 ↗