Drugs / HER2-specific chimeric antigen receptor (CAR) T cell
last change Jan 2024 re-read 3 minutes ago

HER2-specific chimeric antigen receptor (CAR) T cell

Cell therapy

Developed for
atypical teratoid rhabdoid tumor · choroid plexus carcinoma · ependymoma · germ cell tumor · medulloblastoma · pineoblastoma · primitive neuroectodermal tumor
Investigated by
Seattle Children's Hospital

Trials 1

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03500991 Jul 2018 → Jan 2024 overdue atypical teratoid rhabdoid tumor, choroid plexus carcinoma, ependymoma, germ cell tumor +3 Seattle Children's Hospital Active not recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as HER2-specific chimeric antigen receptor (CAR) T cell ClinicalTrials.gov intervention name — accepted as the source's own label NCT03500991 ↗
Modality Cell therapy “Autologous CD4 and CD8 T cells lentivirally transduced to express a HER2 specific chimeric antigen receptor (CAR) and EGFRt” NCT03500991 ↗
Route Other “will then be administered via the indwelling CNS catheter” NCT03500991 ↗