Drugs / Blonanserin
last change Oct 2024 re-read 2 minutes ago

Blonanserin

also known as AD-5423 · Blonanserina · Blonanserine · BNS-P · DSP-5423

Small molecule targets DRD2, DRD3, HTR2A via inhibition

Developed for
schizophrenia
Investigated by
Marubeni Pharmaceuticals (Suzhou) Co., Ltd. · Sumitomo Pharma Co., Ltd.

Trials 3 · a red edge is where a trial was stopped

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 32 trials
Phase 3 NCT02287584 Dec 2014 → Dec 2018 schizophrenia Sumitomo Pharma Co., Ltd. Completed No outcome recorded
Phase 3 NCT01516424 Feb 2012 → Feb 2013 schizophrenia Marubeni Pharmaceuticals (Suzhou) Co., Ltd. Completed No outcome recorded
Phase 41 trial
Phase 4 NCT03784222 Jan 2019 → Nov 2022 CGF1, schizophrenia Marubeni Pharmaceuticals (Suzhou) Co., Ltd. Terminated No outcome recorded

Evidence & citations 12 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Blonanserin “AIM: To explore the optimal dose of blonanserin transdermal patch (BNS-P) based on baseline psychiatric symptomatic characteristics during acute schizophrenia.” PMID 39428614 Oct 2024
2

NCT01516424

NCT03784222

Known as AD-5423 ChEMBL registry synonym — accepted as the source's own label CHEMBL178803
Known as Blonanserina ChEMBL registry synonym — accepted as the source's own label CHEMBL178803
Known as Blonanserine ChEMBL registry synonym — accepted as the source's own label CHEMBL178803
Known as BNS-P “AIM: To explore the optimal dose of blonanserin transdermal patch (BNS-P) based on baseline psychiatric symptomatic characteristics during acute schizophrenia.” PMID 39428614 Oct 2024
Known as DSP-5423 ChEMBL registry synonym — accepted as the source's own label CHEMBL178803
Action Inhibit “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL178803
2

“Dopamine D2 receptor antagonist” CHEMBL178803

“Dopamine D3 receptor antagonist” CHEMBL178803

Modality Small molecule CHEMBL178803
Route Oral “4 mg P.O. twice per day after meals” PMID 35443947 Apr 2022
Target DRD2 “Dopamine D2 receptor antagonist” CHEMBL178803
Target DRD3 “Dopamine D3 receptor antagonist” CHEMBL178803
Target HTR2A “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL178803