Drugs / Squaric Acid Dibutyl Ester
Squaric Acid Dibutyl Ester
Trials 4
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 02 trials | ||||||
| Phase 0 | NCT04999631 | Jan 2027 → Jan 2030 expected | melanocytic nevus | Massachusetts General Hospital | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT05414266 | Aug 2022 → Jun 2023 | alopecia areata | The University of Texas Health Science Center, Houston | Unknown | No outcome recorded |
| Phase 11 trial | ||||||
| Phase 1 | NCT03661541 | Mar → Jun 2017 | herpes labialis | Squarex, LLC | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT03521479 | Mar → Oct 2018 | herpes labialis | Squarex, LLC | Terminated | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 1 | NCT01971385 Comparator | Oct 2013 → Sep 2015 | herpes labialis | Massachusetts General Hospital | Completed | No outcome recorded |
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Squaric Acid Dibutyl Ester | “SADBE 5% is a solution of 5% Squaric Acid Dibutyl Ester (SADBE) in acetone.” NCT05414266 ↗ |
| Known as | Dibutyl squarate | ChEMBL registry synonym — accepted as the source's own label CHEMBL2435707 ↗ |
| Known as | NSC-113489 | ChEMBL registry synonym — accepted as the source's own label CHEMBL2435707 ↗ |
| Known as | SADBE | “Treated with 2% Squaric Acid Dibutyl Ester (SADBE) on day 0 and with 2% SADBE on the visits at week 3, week 6, week 9, and month 8.” NCT03521479 ↗2“Topical squaric acid dibutyl ester (SADBE) dissolved in ethanol at 0.2% concentration.” NCT04999631 ↗ “SADBE 5% is a solution of 5% Squaric Acid Dibutyl Ester (SADBE) in acetone.” NCT05414266 ↗ |
| Known as | SQX770 | ChEMBL registry synonym — accepted as the source's own label CHEMBL2435707 ↗ |
| Modality | Small molecule | — CHEMBL2435707 ↗ |
| Route | Topical | “repeat topical application of 2% and 0.5% squaric acid dibutyl ester (SADBE)” NCT03521479 ↗ |