Drugs / KRAS peptide vaccine

Trials 2

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05013216 Apr 2022 → Oct 2027 expected hereditary neoplastic syndrome, malignant pancreatic neoplasm Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Active not recruiting No outcome recorded
Phase 1 NCT04117087 May 2020 → Jun 2027 expected colorectal cancer, malignant pancreatic neoplasm Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as KRAS peptide vaccine “Drug: up to 1.8 mg KRAS peptide vaccine + 0.5mg Poly-ICLC” NCT05013216 ↗
1

NCT04117087 ↗

Known as pooled mutant-KRAS peptide vaccine “This study will evaluate safety and the immune response to pooled mutant-KRAS peptide vaccine (KRAS peptide vaccine) with poly-ICLC adjuvant.” NCT05013216 ↗
Modality Vaccine “pooled synthetic long peptide vaccine targeting the six KRAS mutations” PMID 41667470 ↗ Feb 2026
Target KRAS “pooled synthetic long peptide vaccine targeting the six KRAS mutations” PMID 41667470 ↗ Feb 2026