Drugs / Haloperidol Decanoate
last change Jul 2020 re-read 2 minutes ago

Haloperidol Decanoate

also known as Haldol dec · Halomonth · R-13,672

Small molecule targets HTR2A via inhibition

Developed for
schizoaffective disorder · schizophrenia
Investigated by
Case Western Reserve University · National Institute of Mental Health (NIMH) · US Department of Veterans Affairs

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) HALDOL 1986-01-14 fda.gov

Trials 2 · a red edge is where a trial was stopped

1985198619871988198919901991199219931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 31 trial
Phase 3 NCT04327843 Nov 2019 → Jul 2020 schizoaffective disorder, schizophrenia Case Western Reserve University Completed No outcome recorded
Phase not applicable1 trial
NCT00018642 Apr 1997 → Mar 2002 schizoaffective disorder, schizophrenia US Department of Veterans Affairs Completed No outcome recorded
Also used as a comparator or background therapy in 3 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT01949662 Background Jan 2014 → Aug 2016 overdue high grade malignant neoplasm M.D. Anderson Cancer Center Active not recruiting No outcome recorded
Phase 42 trials
Phase 4 NCT01136772 Comparator Mar 2011 → Jul 2013 schizoaffective disorder, schizophrenia New York State Psychiatric Institute Completed No outcome recorded
Phase 4 NCT00947375 Background Jan 2005 → Jan 2006 schizophrenia Central Mental Clinic for Outpatients of Baku City Terminated No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as haloperidol decanoate ClinicalTrials.gov intervention name — accepted as the source's own label NCT01136772
4

NCT01949662

NCT04327843

NCT00947375

NCT00018642

Known as Haldol dec ChEMBL registry synonym — accepted as the source's own label CHEMBL1200986
Known as Halomonth ChEMBL registry synonym — accepted as the source's own label CHEMBL1200986
Known as R-13,672 ChEMBL registry synonym — accepted as the source's own label CHEMBL1200986
Action Inhibit “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL1200986
Modality Small molecule CHEMBL1200986
Route Intramuscular “haloperidol deaconate 50 mg in weekly intramuscularNCT00947375
Target HTR2A “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL1200986