Drugs / CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T cells
last change Jun 2014 re-read 3 minutes ago

CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T cells

Cell therapy targets CD19

Developed for
diffuse large B-cell lymphoma · mantle cell lymphoma
Investigated by
City of Hope Medical Center · National Cancer Institute (NCI)

Trials 1

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02051257 Jun 2014 → Mar 2027 expected diffuse large B-cell lymphoma, mantle cell lymphoma City of Hope Medical Center Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT02051257 ↗
Modality Cell therapy “Memory enriched T cells will be made from a patient's own T cells that are genetically modified in a laboratory.” NCT02051257 ↗
Route Intravenous “Patients receive autologous CD19CAR-CD28-CD3zeta-EGFRt-expressing TCM-enriched T cells intravenously (IV) over 10 minutes on day 2 or 3 following HSCT.” NCT02051257 ↗
Target CD19 “CD19-Specific” NCT02051257 ↗