Drugs / LINVENCORVIR
last change Jul 2024 re-read 2 minutes ago

LINVENCORVIR

also known as RO7049389 · RG-7907

Small molecule

Developed for
chronic hepatitis B virus infection
Investigated by
Hoffmann-La Roche

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT04729309 Mar → Jun 2021 Hoffmann-La Roche Completed No outcome recorded
Phase 1 NCT03717064 Nov → Dec 2018 Hoffmann-La Roche Completed No outcome recorded
Phase 1 NCT03570658 Aug 2018 → Jan 2019 hepatitis B virus infection Hoffmann-La Roche Completed No outcome recorded
Phase 1 NCT02952924 Dec 2016 → Mar 2022 chronic hepatitis B virus infection Hoffmann-La Roche Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04225715 Jul 2020 → Jul 2024 chronic hepatitis B virus infection Hoffmann-La Roche Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as LINVENCORVIR ChEMBL registry synonym — accepted as the source's own label CHEMBL5095071
Known as RG-7907 ChEMBL registry synonym — accepted as the source's own label CHEMBL5095071
Known as RO7049389 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03570658
4

NCT04225715

NCT04729309

NCT03717064

NCT02952924

Action Inhibit “RO7049389, an inhibitor of hepatitis B virus (HBV) capsid assembly” PMID 32839221 Oct 2020
Modality Small molecule CHEMBL5095071
Route Oral “RO7049389 will be administered orally either as a single dose (SAD) or as multiple doses defined by the SAD portion of the study (MAD).” NCT03570658