Drugs / WX-554
last change Apr 2014 re-read 3 minutes ago

WX-554

targets MAP2K1, MAP2K2 via inhibition

Developed for
cancer
Investigated by
Heidelberg Pharma AG

Trials 2

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01859351 Jul 2013 → Apr 2014 cancer Heidelberg Pharma AG Terminated No outcome recorded Stop: Business
Phase 1/21 trial
Phase 1/2 NCT01581060 Mar 2012 → Apr 2014 cancer Heidelberg Pharma AG Terminated No outcome recorded Stop: Business

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as WX-554 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01859351 ↗
1

NCT01581060 ↗

Action Inhibit “Dual specificity mitogen-activated protein kinase kinase 2 inhibitor” CHEMBL3545145 ↗
2

“Dual specificity mitogen-activated protein kinase kinase 1 inhibitor” CHEMBL3545145 ↗

“the MEK Inhibitor WX-554” NCT01581060 ↗

Target MAP2K1 “Dual specificity mitogen-activated protein kinase kinase 1 inhibitor” CHEMBL3545145 ↗
Target MAP2K2 “Dual specificity mitogen-activated protein kinase kinase 2 inhibitor” CHEMBL3545145 ↗