Drugs / Cicletanine
Cicletanine
also known as
(+/-)BN-1270 · Cicletanina · cicletanine HCl · cicletanine hydrochloride (HCl) · Cycletanide · WIN 90,000
Trials 1 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2 | NCT00832507 | Jan 2009 → Oct 2011 | pulmonary arterial hypertension | Gilead Sciences | Terminated | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/2 | NCT02709031 Comparator | Jun 2022 → Jun 2024 | diabetes mellitus, hypertensive disorder, potassium deficiency | Navitas Pharma | Unknown | No outcome recorded |
Press releases naming this drug 2 releases
| Date | Issuer | Release |
|---|---|---|
| 2009-03-24 | Gilead Sciences | Gilead Initiates Phase II Clinical Trial of Cicletanine for the Treatment of Pulmonary Arterial Hypertension gilead.com ↗ |
| 2008-05-29 | Gilead Sciences | Gilead and Navitas Announce Agreement for Cicletanine for the Treatment of Pulmonary Arterial Hypertension gilead.com ↗ |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Cicletanine | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00832507 ↗ |
| Known as | (+/-)BN-1270 | ChEMBL registry synonym — accepted as the source's own label CHEMBL191886 ↗ |
| Known as | Cicletanina | ChEMBL registry synonym — accepted as the source's own label CHEMBL191886 ↗ |
| Known as | cicletanine HCl | “The primary objective of this study is to compare the change in exercise capacity following treatment with cicletanine HCl or placebo in subjects with PAH.” NCT00832507 ↗ |
| Known as | cicletanine hydrochloride (HCl) | “This Phase 2, randomized, double-blind, placebo-controlled, multicenter, dose-ranging study will compare the efficacy, safety, and tolerability of cicletanine hydrochloride...” NCT00832507 ↗ |
| Known as | Cycletanide | ChEMBL registry synonym — accepted as the source's own label CHEMBL191886 ↗ |
| Known as | WIN 90,000 | ChEMBL registry synonym — accepted as the source's own label CHEMBL191886 ↗ |
| Modality | Small molecule | “orally-dosed furopyridine drug” NCT02709031 ↗ |
| Route | Oral | “Cicletanine capsules 150 mg or 300 mg administered orally once or twice daily” NCT00832507 ↗ |