Drugs / Anbalcabtagene autoleucel
last change Jun 2026 re-read 3 minutes ago

Anbalcabtagene autoleucel

also known as Anbal-cel

Cell therapy targets TIGIT via inhibition

Developed for
B-cell acute lymphoblastic leukemia · follicular lymphoma · high grade B-cell lymphoma · large B-cell lymphoma · primary mediastinal large B-cell lymphoma
Investigated by
Curocell Inc.

Trials 1

2021202220232024202520262027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT04836507 Mar 2021 → Aug 2030 expected B-cell acute lymphoblastic leukemia, follicular lymphoma, high grade B-cell lymphoma, large B-cell lymphoma +1 Curocell Inc. Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Anbalcabtagene autoleucel “Anbalcabtagene autoleucel (Anbal-cel) is a CD19-directed CAR T-cell therapy incorporating dual PD-1 and TIGIT knockdown to enhance antitumor function and durability.” PMID 42284198 ↗ Jun 2026
Known as Anbal-cel “Anbalcabtagene autoleucel (Anbal-cel) is a CD19-directed CAR T-cell therapy incorporating dual PD-1 and TIGIT knockdown to enhance antitumor function and durability.” PMID 42284198 ↗ Jun 2026
Action Inhibit “incorporating dual PD-1 and TIGIT knockdown to enhance antitumor function and durability” PMID 42284198 ↗ Jun 2026
Modality Cell therapy “Anbalcabtagene autoleucel (Anbal-cel) is a CD19-directed CAR T-cell therapy” PMID 42284198 ↗ Jun 2026
Route Intravenous “administered intravenously at a target dose of 2 x 10\^6 anti-CD19 CAR T cells/kg” NCT04836507 ↗
Target TIGIT “Anbalcabtagene autoleucel (Anbal-cel) is a CD19-directed CAR T-cell therapy incorporating dual PD-1 and TIGIT knockdown” PMID 42284198 ↗ Jun 2026