Drugs / TIDUTAMAB
last change Mar 2022 re-read 3 minutes ago

TIDUTAMAB

also known as XmAb18087

Monoclonal antibody

Developed for
cutaneous neuroendocrine carcinoma · digestive system neoplasm · neuroendocrine neoplasm · small cell lung carcinoma
Investigated by
ICON plc · Xencor, Inc.

Trials 2

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03411915 Jan 2018 → Oct 2021 digestive system neoplasm, neuroendocrine neoplasm Xencor, Inc. Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT04590781 May 2021 → Mar 2022 cutaneous neuroendocrine carcinoma, small cell lung carcinoma Xencor, Inc. Terminated No outcome recorded Stop: Business

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2017-03-01 Xencor, Inc. Results Xencor Presents Preclinical Data on Emerging Bispecific Antibody Candidates at American Association for Cancer Research (AACR) 2017 Annual Meeting xencor.com ↗
Anti-SSTR2 × anti-CD3 bispecific antibody induces potent killing of human tumor cells in vitro and in mice, and stimulates target-dependent T cell activation in monkeys: A potential immunotherapy for neuroendocrine tumors

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as TIDUTAMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL4298132 ↗
Known as XmAb18087 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03411915 ↗
1

NCT04590781 ↗

Modality Monoclonal antibody “monoclonal bispecific antibody” NCT03411915 ↗