Drugs / 18F-SF12051
last change Dec 2024 re-read 3 minutes ago

18F-SF12051

Diagnostic / imaging agent targets TSPO

Investigated by
National Institute of Mental Health (NIMH)

Trials 1

2023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05564429 Feb → May 2023 — National Institute of Mental Health (NIMH) Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as 18F-SF12051 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05564429 ↗
Modality Diagnostic / imaging agent “[(18)F]SF51, a novel (18)F-labeled PET radioligand for translocator protein 18kDa (TSPO) in brain, works well in monkeys but fails in humans.” PMID 39654356 ↗ Dec 2024
Route Intravenous “Healthy participants with HAB TSPO genotype receive 18F-SF12051 intravenously followed by whole body or brain positron emission tomography (PET) scan.” NCT05564429 ↗
Target TSPO “[18F]SF51 is a novel radioligand for imaging translocator protein 18 kDa (TSPO) that previously displayed excellent imaging properties in nonhuman primates.” PMID 39654356 ↗ Dec 2024