Drugs / Parathyroid Hormone-related Protein (1-36)
last change Jul 2017 re-read 2 minutes ago

Parathyroid Hormone-related Protein (1-36)

also known as hPTHrP(1-36) · PTHrP (1-36)

Peptide

Developed for
osteoporosis
Investigated by
University of Pittsburgh · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · National Institutes of Health (NIH)

Trials 3 · a red edge is where a trial was stopped

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT00580788 Jan 2008 → Dec 2009 humoral hypercalcemia of malignancy, hyperparathyroidism, osteoporosis University of Pittsburgh Completed No outcome recorded
Phase 11 trial
Phase 1 NCT01333267 Jan 2015 → Jul 2017 humoral hypercalcemia of malignancy, hyperparathyroidism, osteoporosis University of Pittsburgh Withdrawn No outcome recorded
Phase 21 trial
Phase 2 NCT00853723 May 2009 → Feb 2012 osteoporosis University of Pittsburgh Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Parathyroid Hormone-related Protein (1-36) ClinicalTrials.gov intervention name — accepted as the source's own label NCT01333267
1

NCT00853723

Known as hPTHrP(1-36) “We therefore developed 7-day continuous-infusion models using human parathyroid hormone(1-34) [hPTH(1-34)] and human parathyroid hormone-related protein(1-36) [hPTHrP(1-36)] in...” PMID 21544866 Sep 2011
Known as PTHrP (1-36) ClinicalTrials.gov intervention name — accepted as the source's own label NCT00580788
Action Activate “Both peptides bind to the same receptor, PTH-1 R, and activate downstream signaling pathways” NCT00853723
Modality Protein / enzyme biologic “human parathyroid hormone-related protein(1-36)” PMID 21544866 Sep 2011
Route Intravenous “continuous intravenous manner” NCT00580788