Drugs / Bindarit
last change Apr 2011 re-read 3 minutes ago

Bindarit

also known as AF 2838

Small molecule targets CCL7, CCL8 via inhibition

Developed for
coronary restenosis · diabetic kidney disease
Investigated by
Angelini Pharma · Mario Negri Institute for Pharmacological Research

Trials 2

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01269242 Jan 2009 → Jan 2011 coronary restenosis Angelini Pharma Completed No outcome recorded
Phase 2 NCT01109212 Mar 2007 → Nov 2008 diabetic kidney disease Angelini Pharma Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as bindarit ClinicalTrials.gov intervention name — accepted as the source's own label NCT01269242 ↗
1

NCT01109212 ↗

Known as AF 2838 ChEMBL registry synonym — accepted as the source's own label CHEMBL2107549 ↗
Action Inhibit “a selective inhibitor of MCP-1 and other members of monocyte chemotactic protein subfamily of CC inflammatory chemokines (MCP-3/CCL7, MCP-2/CCL8), such as bindarit” NCT01269242 ↗
Modality Small molecule — CHEMBL2107549 ↗
Target CCL7 “a selective inhibitor of MCP-1 and other members of monocyte chemotactic protein subfamily of CC inflammatory chemokines (MCP-3/CCL7, MCP-2/CCL8), such as bindarit” NCT01269242 ↗
Target CCL8 “a selective inhibitor of MCP-1 and other members of monocyte chemotactic protein subfamily of CC inflammatory chemokines (MCP-3/CCL7, MCP-2/CCL8), such as bindarit” NCT01269242 ↗