Drugs / Tigulixostat
last change Mar 2026 re-read 2 minutes ago

Tigulixostat

also known as LC350189 · IBI128

Small molecule

Developed for
gout
Investigated by
LG Chem · Innovent Biologics (Suzhou) Co. Ltd. · Innovent Biologics Technology Limited (Shanghai R&D Center) · LG Life Sciences

Trials 13 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT04966325 Sep → Dec 2021 gout LG Chem Completed No outcome recorded
Phase 17 trials
Phase 1 NCT06277752 Mar 2024 gout Innovent Biologics (Suzhou) Co. Ltd. Completed No outcome recorded
Phase 1 NCT06189404 Oct → Nov 2023 gout LG Chem Completed No outcome recorded
Phase 1 NCT04070846 Feb → Mar 2020 gout LG Chem Completed No outcome recorded
Phase 1 NCT04139824 Jan → Feb 2020 gout LG Chem Completed No outcome recorded
Phase 1 NCT04066712 Nov 2019 → Sep 2020 gout LG Chem Completed No outcome recorded
Phase 1 NCT03927677 Nov 2019 gout LG Chem Completed No outcome recorded
Phase 1 NCT01361646 Jun 2011 → Jan 2013 gout LG Life Sciences Completed No outcome recorded
Phase 22 trials
Phase 2 NCT06501534 Jul → Dec 2024 gout Innovent Biologics (Suzhou) Co. Ltd. Completed No outcome recorded
Phase 2 NCT03934099 Dec 2019 → May 2021 gout LG Chem Completed No outcome recorded
Phase 33 trials
Phase 3 NCT07414394 Mar 2026 → Apr 2027 expected gout Innovent Biologics Technology Limited (Shanghai R&D Center) Recruiting No outcome recorded
Phase 3 NCT05586971 Mar 2023 → May 2025 gout LG Chem Completed No outcome recorded
Phase 3 NCT05586958 Oct 2022 → Nov 2024 gout LG Chem Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04886050 Comparator Jul → Sep 2021 gout LG Chem Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 15 sources stand behind the page.

FieldValueCited text
Known as Tigulixostat ClinicalTrials.gov intervention name — accepted as the source's own label NCT05586958
3

NCT07414394

NCT06189404

NCT05586971

Known as IBI128 “Participants in this group receive Tigulixostat (IBI128) tablets together with dummy tablets matching Febuxostat once daily during the 24-week core treatment period, with dose...” NCT07414394
2

IBI128 300mg po. QD(Quaque Die)” NCT06277752

NCT06501534

Known as LC350189 LC350189 200mg qd” NCT04139824
8

LC350189 200mg qd” NCT03927677

LC350189NCT04139824

NCT04066712

NCT03934099

NCT04070846

NCT01361646

NCT04886050

NCT04966325

Action Inhibit “Xanthine Oxidase Inhibitor” NCT03934099
Modality Small molecule CHEMBL3652780
Route Oral “by oralNCT04066712