Drugs / DC371739
last change Apr 2022 re-read 3 minutes ago

DC371739

Small molecule targets ANGPTL3, PCSK9 via inhibition

Developed for
hyperlipidemia
Investigated by
Guangzhou JOYO Pharma Co., Ltd · The First Hospital of Jilin University

Trials 2

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04927221 Apr → Dec 2021 hyperlipidemia Guangzhou JOYO Pharma Co., Ltd Completed No outcome recorded
Phase 1 NCT04640012 Sep 2020 → Mar 2021 hyperlipidemia Guangzhou JOYO Pharma Co., Ltd Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as DC371739 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04927221 ↗
1

NCT04640012 ↗

Action Inhibit “impeding the transcription of both PCSK9 and ANGPTL3” PMID 35427476 ↗ Apr 2022
Modality Small molecule “an indole-containing tetrahydroisoquinoline compound” PMID 35427476 ↗ Apr 2022
Route Oral “single-dose oral administration” NCT04640012 ↗
Target ANGPTL3 “impeding the transcription of both PCSK9 and ANGPTL3” PMID 35427476 ↗ Apr 2022
Target PCSK9 “impeding the transcription of both PCSK9 and ANGPTL3” PMID 35427476 ↗ Apr 2022