Drugs / RG547
last change Nov 2008 re-read 3 minutes ago

RG547

also known as R 547 · RO4584820

Small molecule targets CDK1, CDK2, CDK4 via inhibition

Developed for
neoplasm
Investigated by
Hoffmann-La Roche

Trials 1

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00400296 May 2005 → Nov 2008 neoplasm Hoffmann-La Roche Completed No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as RG547 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00400296 ↗
Known as R 547 ChEMBL registry synonym — accepted as the source's own label CHEMBL384304 ↗
Known as RO4584820 ChEMBL registry synonym — accepted as the source's own label CHEMBL384304 ↗
Action Inhibit “Cyclin-dependent kinase 2 inhibitor” CHEMBL384304 ↗
2

“Cyclin-dependent kinase 4 inhibitor” CHEMBL384304 ↗

“Cyclin-dependent kinase 1 inhibitor” CHEMBL384304 ↗

Modality Small molecule — CHEMBL384304 ↗
Route Intravenous “Administered as an Intravenous Infusion” NCT00400296 ↗
Target CDK1 “Cyclin-dependent kinase 1 inhibitor” CHEMBL384304 ↗
Target CDK2 “Cyclin-dependent kinase 2 inhibitor” CHEMBL384304 ↗
Target CDK4 “Cyclin-dependent kinase 4 inhibitor” CHEMBL384304 ↗