Drugs / TAVOLIMAB

Trials 3 · a red edge is where a trial was stopped

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02705482 Mar 2016 → Aug 2019 cancer MedImmune LLC Completed No outcome recorded
Phase 1 NCT02318394 Mar 2015 → Jan 2018 cancer MedImmune LLC Completed No outcome recorded
Phase 21 trial
Phase 2 NCT03267589 May 2018 → Oct 2021 ovarian cancer Nordic Society of Gynaecological Oncology - Clinical Trials Unit Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03336606 Comparator Jul 2018 → Jun 2025 head and neck squamous cell carcinoma, melanoma Providence Health & Services Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as TAVOLIMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL4298028
Known as MEDI0562 “Intervention: MEDI0562 (OX40) + durvalumab” NCT03267589
4

NCT03267589

NCT02318394

NCT03336606

NCT02705482

Known as Tavolixizumab ChEMBL registry synonym — accepted as the source's own label CHEMBL4298028
Action Activate “MEDI0562, an agonistic humanized mAb, specifically binds to the costimulatory molecule OX40.” PMID 32816951 Aug 2020
Modality Monoclonal antibody “MEDI0562, an agonistic humanized mAb, specifically binds to the costimulatory molecule OX40.” PMID 32816951 Aug 2020
Route Intravenous “every 4 weeks, intravenously” PMID 35699623 Sep 2022