Drugs / MB-CART2019.1
last change Apr 2026 re-read 2 minutes ago

MB-CART2019.1

Cell therapy

Developed for
diffuse large B-cell lymphoma · multiple sclerosis · B-cell non-Hodgkin lymphoma
Investigated by
Miltenyi Biomedicine GmbH · ICON plc

Trials 4 · a red edge is where a trial was stopped

20222023202420252026202720282029203020312032203320342035203620372038203920402041
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT07178431 Apr 2026 → Aug 2030 expected multiple sclerosis Miltenyi Biomedicine GmbH Recruiting No outcome recorded
Phase 22 trials
Phase 2 NCT07288879 Dec 2025 → Jan 2027 expected diffuse large B-cell lymphoma Miltenyi Biomedicine GmbH Recruiting No outcome recorded
Phase 2 NCT04844866 Aug 2021 → Jan 2025 overdue diffuse large B-cell lymphoma Miltenyi Biomedicine GmbH Recruiting No outcome recorded
Phase not applicable1 trial
NCT06508775 May 2024 → Dec 2040 expected childhood acute lymphoblastic leukemia, chronic lymphocytic leukemia/small lymphocytic lymphoma, melanoma Miltenyi Biomedicine GmbH Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as MB-CART2019.1 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07288879
3

NCT07178431

NCT04844866

NCT06508775

Known as zamtocabtagene autoleucel “DALY II Japan is a phase II, multi-center, single arm study to evaluate the efficacy, safety, and pharmacokinetics of zamtocabtagene autoleucel (MB-CART2019.1) in patients with...” NCT07288879
Modality Cell therapy “MB-CART2019.1 consists of autologous cluster of differentiation CD20/CD19 chimeric antigen receptor (CAR) transduced CD4/CD8 enriched T cells” NCT04844866
Route Intravenous “Cell infusion will be administered intravenously” NCT07288879