Drugs / Elsubrutinib
last change Jan 2024 re-read 2 minutes ago

Elsubrutinib

also known as ABBV-105

Small molecule targets BTK via inhibition

Developed for
rheumatoid arthritis · systemic lupus erythematosus
Investigated by
AbbVie

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT04451772 Jul 2020 → Jan 2024 systemic lupus erythematosus AbbVie Completed No outcome recorded
Phase 2 NCT03978520 Jul 2019 → Jan 2022 systemic lupus erythematosus AbbVie Completed No outcome recorded
Phase 2 NCT03823378 May 2019 → Sep 2020 rheumatoid arthritis AbbVie Terminated No outcome recorded
Phase 2 NCT03682705 Oct 2018 → Mar 2020 rheumatoid arthritis AbbVie Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Elsubrutinib ClinicalTrials.gov intervention name — accepted as the source's own label NCT03978520
3

NCT04451772

NCT03823378

NCT03682705

Known as ABBV-105 ChEMBL registry synonym — accepted as the source's own label CHEMBL4594348
Action Inhibit “the Bruton's tyrosine kinase (BTK) inhibitor elsubrutinib” PMID 38293957 Apr 2022
Modality Small molecule CHEMBL4594348
Route Oral “Elsubrutinib capsule will be administered orally.” NCT03682705
Target BTK “the Bruton's tyrosine kinase (BTK) inhibitor elsubrutinib” PMID 38293957 Apr 2022