Drugs / HRS-1780
last change Jul 2026 re-read 2 minutes ago

HRS-1780

also known as [14C]HRS-1780

Small molecule

Developed for
chronic kidney disease · primary aldosteronism · resistant hypertension
Investigated by
Shandong Suncadia Medicine Co., Ltd.

Trials 9 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT07557407 May → Jun 2026 overdue chronic kidney disease Shandong Suncadia Medicine Co., Ltd. Not yet recruiting No outcome recorded
Phase 1 NCT06495931 Jul → Aug 2024 type 2 diabetes mellitus Shandong Suncadia Medicine Co., Ltd. Completed No outcome recorded
Phase 1 NCT06344936 Apr → Jul 2024 chronic kidney disease Shandong Suncadia Medicine Co., Ltd. Unknown No outcome recorded
Phase 1 NCT06039254 Sep → Nov 2023 chronic kidney disease Shandong Suncadia Medicine Co., Ltd. Unknown No outcome recorded
Phase 1 NCT05638126 Feb → Dec 2023 chronic kidney disease Shandong Suncadia Medicine Co., Ltd. Unknown No outcome recorded
Phase 22 trials
Phase 2 NCT07470983 Apr → Nov 2026 expected primary aldosteronism Shandong Suncadia Medicine Co., Ltd. Recruiting No outcome recorded
Phase 2 NCT06221059 Mar 2024 → Mar 2025 chronic kidney disease Shandong Suncadia Medicine Co., Ltd. Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT07708441 Jul 2026 → Apr 2029 expected resistant hypertension Shandong Suncadia Medicine Co., Ltd. Not yet recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT07419828 Mar 2026 → Apr 2030 expected chronic kidney disease Shandong Suncadia Medicine Co., Ltd. Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 10 sources stand behind the page.

FieldValueCited text
Known as HRS-1780 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06039254
8

NCT07557407

NCT06344936

NCT07470983

NCT05638126

NCT06221059

NCT06495931

NCT07419828

NCT07708441

Known as [14C]HRS-1780 “A Mass Balance Study of [14C]HRS-1780 in Healthy Adult Male Subjects” NCT07557407
Action Inhibit “HRS-1780, a selective non-steroidal mineralocorticoid receptor antagonist” PMID 39155700 Aug 2024
Modality Small molecule “an oral selective non-steroidal mineralocorticoid receptor antagonist” PMID 39155700 Aug 2024
Route Oral “an oral selective non-steroidal mineralocorticoid receptor antagonist” PMID 39155700 Aug 2024