Drugs / Cytogam
Cytogam
also known as
CMV hyperimmune globulin · CMVIg · Cytotect · Cytomegalovirus Immune Globulin Intravenous (Human)
Trials 6 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT07096453 | Oct 2025 → Aug 2027 expected | cytomegalovirus infection | University of Minnesota | Recruiting | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT04934527 | Nov 2021 → Dec 2024 | cytomegalovirus infection | University Hospital, Bordeaux | Completed | No outcome recorded |
| Phase 2/32 trials | ||||||
| Phase 2/3 | NCT00881517 | Jun 2009 → Oct 2011 | cytomegalovirus infection | Fondazione IRCCS Policlinico San Matteo di Pavia | Completed | No outcome recorded |
| Phase 2/3 | NCT00137748 | Jan 2001 → Jan 2006 | dysgammaglobulinemia | The Cleveland Clinic | Completed | No outcome recorded |
| Phase 42 trials | ||||||
| Phase 4 | NCT06958796 | Nov 2025 → Dec 2027 expected | cytomegalovirus infection, disease related to solid organ transplantation | Camille N. Kotton, MD | Recruiting | No outcome recorded |
| Phase 4 | NCT07009548 | Jun 2025 → Dec 2027 expected | cytomegalovirus infection | Fernanda P Silveira, MD, MS | Enrolling by invitation | No outcome recorded |
Also used as a comparator or background therapy in 3 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 32 trials | ||||||
| Phase 3 | NCT01376778 Comparator | Apr 2012 → Oct 2019 | cytomegalovirus infection | The George Washington University Biostatistics Center | Completed | No outcome recorded |
| Phase 3 | NCT00275509 Background | Jan 2007 → Jun 2010 | chronic renal failure syndrome | Johns Hopkins University | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT01509404 Comparator | Nov 2011 → Dec 2014 | cytomegalovirus infection | Medical University of South Carolina | Completed | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 9 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | CytoGam | “CytoGam - Cytomegalovirus Immune Globulin Intravenous (CMV-IGIV), is an immunoglobulin G containing a standardized amount of antibody against CMV.” NCT07009548 ↗ |
| Known as | CMV hyperimmune globulin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01509404 ↗ |
| Known as | CMVIg | “100 mg/kg of Cytogam (CMVIg) (Cytogam, CSL Behring, King of Prussia, PA) was administered” NCT00275509 ↗ |
| Known as | Cytomegalovirus Immune Globulin Intravenous (Human) | ClinicalTrials.gov intervention name — accepted as the source's own label NCT06958796 ↗ |
| Known as | Cytotect | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00881517 ↗ |
| Action | Activate | “The anti-CMV IgGs capturing virions thus activate CD16+ LTgdVd2neg with production of IFN interferon which in turn is responsible for inhibition of CMV viral multiplication.” NCT04934527 ↗ |
| Modality | Protein / enzyme biologic | “intravenous immunoglobulin infusion” NCT00275509 ↗ |
| Route | Intravenous | “receive Cytotect® or placebo intravenously” NCT00881517 ↗ |