Drugs / sabirnetug
last change Jan 2025 re-read 2 minutes ago

sabirnetug

also known as ACU193

Monoclonal antibody

Developed for
Alzheimer disease
Investigated by
Acumen Pharmaceuticals · National Institute on Aging (NIA)

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06511570 Jun → Sep 2024 Alzheimer disease Acumen Pharmaceuticals Completed No outcome recorded
Phase 1 NCT04931459 Jun 2021 → Jun 2023 Alzheimer disease Acumen Pharmaceuticals Completed No outcome recorded
Phase 21 trial
Phase 2 NCT06335173 Feb 2024 → Oct 2026 expected Alzheimer disease Acumen Pharmaceuticals Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as sabirnetug ClinicalTrials.gov intervention name — accepted as the source's own label NCT06335173
1

NCT06511570

Known as ACU193 “Sabirnetug (ACU193) is a humanized monoclonal antibody, raised against globular species of soluble AβO, that has over 650-fold greater binding affinity for AβOs over monomers...” PMID 39800458 Jan 2025
2

“sabirnetug (ACU193)” NCT06511570

NCT04931459

Modality Monoclonal antibody “Sabirnetug (ACU193) is a humanized monoclonal antibodyPMID 39800458 Jan 2025
Route Intravenous “by intravenous (IV) infusion” NCT04931459