Drugs / RIV4
last change Dec 2025 re-read 2 minutes ago

RIV4

also known as QIVr · Supemtek

Vaccine

Developed for
influenza
Investigated by
Sanofi Pasteur, a Sanofi Company

Trials 1 · a red edge is where a trial was stopped

2023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT05513053 Oct 2022 → Oct 2023 Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Also used as a comparator or background therapy in 4 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06850051 Comparator Mar → Dec 2025 parainfluenza infectious disease, respiratory syncytial virus infectious disease Sanofi Completed No outcome recorded
Phase 1 NCT05829356 Comparator Apr 2023 → Mar 2024 Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT05624606 Comparator Nov 2022 → Mar 2024 Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04576702 Comparator Oct 2020 → Mar 2021 influenza Seqirus Completed No outcome recorded

Press releases naming this drug 2 releases

DateIssuerRelease
2020-11-18 Sanofi European Commission approves Supemtek® (quadrivalent recombinant influenza vaccine) for the prevention of influenza in adults aged 18 years and older sanofi.com
2020-09-22 Sanofi CHMP recommends approval of Supemtek® (quadrivalent recombinant influenza vaccine) for the prevention of influenza in adults aged 18 years and older sanofi.com

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as RIV4 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05513053
4

NCT05624606

NCT05829356

NCT04576702

NCT06850051

Known as QIVr “Eligible participants aged ≥50 years were randomised 1: 1:1:1 to receive aQIVc (n = 116), a non-adjuvanted quadrivalent cell-based influenza vaccine (QIVc; n = 119), an...” PMID 39946829 Feb 2025
Known as Supemtek “RIV4 (Supemtek®)” NCT06850051
Modality Vaccine “Licensed, Recombinant Quadrivalent Influenza VaccineNCT04576702
Route Intramuscular “RIV4 will be administered as a single dose intramuscularly on Day 1” NCT04576702