Drugs / AB002
last change Jul 2024 re-read 3 minutes ago

AB002

also known as E-WE thrombin

Protein / enzyme biologic

Developed for
thrombotic disease
Investigated by
Aronora, Inc. · Celerion

Trials 1

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT03963895 Jul 2019 → Dec 2020 end stage renal failure, thrombotic disease Aronora, Inc. Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as AB002 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03963895 ↗
Known as E-WE thrombin “AB002 (E-WE thrombin) is an investigational protein C activator thrombin analog in phase 2 clinical development” PMID 31977000 ↗ Feb 2020
Action Activate “AB002 is an injectable protein C activating enzyme under investigation to safely prevent and treat thrombosis.” PMID 39060370 ↗ Jul 2024
Modality Protein / enzyme biologic “AB002 is an injectable protein C activating enzyme under investigation to safely prevent and treat thrombosis.” PMID 39060370 ↗ Jul 2024
Route Intravenous “AB002 (E-WE thrombin) 1.5 mcg/kg administered on Day 1 as a single intravenous infusion” NCT03963895 ↗