Drugs / CC-401
last change Sep 2006 re-read 3 minutes ago

CC-401

Small molecule targets MAPK10, MAPK8, MAPK9 via inhibition

Developed for
myeloid leukemia
Investigated by
Celgene Corporation

Trials 1

2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00126893 Oct 2005 → Sep 2006 myeloid leukemia Celgene Corporation Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as CC-401 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00126893 ↗
Action Inhibit “c-Jun N-terminal kinase 3 inhibitor” CHEMBL1614713 ↗
2

“c-Jun N-terminal kinase 2 inhibitor” CHEMBL1614713 ↗

“c-Jun N-terminal kinase 1 inhibitor” CHEMBL1614713 ↗

Modality Small molecule — CHEMBL1614713 ↗
Target MAPK10 “c-Jun N-terminal kinase 3 inhibitor” CHEMBL1614713 ↗
Target MAPK8 “c-Jun N-terminal kinase 1 inhibitor” CHEMBL1614713 ↗
Target MAPK9 “c-Jun N-terminal kinase 2 inhibitor” CHEMBL1614713 ↗