Drugs / BI 905711
last change Nov 2023 re-read 9 days ago

BI 905711

targets CDH17 via activation

Developed for
cholangiocarcinoma · digestive system cancer · pancreatic neoplasm
Investigated by
Boehringer Ingelheim

Trials 2

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05087992 Nov 2021 → Oct 2023 digestive system cancer Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT04137289 Mar 2020 → Jul 2023 cholangiocarcinoma, pancreatic neoplasm Boehringer Ingelheim Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as BI 905711 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05087992 ↗
1

NCT04137289 ↗

Action Activate “BI 905711 is a novel tetravalent bispecific antibody targeting both TRAILR2 and CDH17 and represents a novel liver-sparing TRAILR2 agonist specifically designed to overcome the...” PMID 33037135 ↗ Oct 2020
Route Intravenous “BI 905711 intravenously” NCT04137289 ↗
Target CDH17 “BI 905711 is a novel tetravalent bispecific antibody targeting both TRAILR2 and CDH17 and represents a novel liver-sparing TRAILR2 agonist specifically designed to overcome the...” PMID 33037135 ↗ Oct 2020