Drugs / RN5681
last change Mar 2026 re-read 3 minutes ago

RN5681

Investigated by
Ikaria Bioscience Pty Ltd · Shanghai Rona Therapeutics Co., Ltd.

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07347678 Mar 2026 → Feb 2027 expected — Ikaria Bioscience Pty Ltd Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2025-12-17 Shanghai Rona Therapeutics Co., Ltd. Regulatory Rona Therapeutics Unveils the Global First Bi-valent PCSK9-LPA siRNA into Clinical Development for Cardiovascular Risk Reduction ronatherapeutics.com ↗
Shanghai, China; California, US — December 17, 2025 — Rona Therapeutics , a global leader in next-generation RNAi medicines, today announced the submission of RN5681 to the Australian Human Research Ethics Committee (HREC), advancing the company’s first bi-valent siRNA into clinical development.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as RN5681 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07347678 ↗
Route Subcutaneous “Drug: RN5681 Investigational product subcutaneous injections” NCT07347678 ↗