Drugs / SB-728mR-HSPC
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SB-728mR-HSPC

Cell therapy targets CCR5 via inhibition

Developed for
HIV infectious disease
Investigated by
California Institute for Regenerative Medicine (CIRM) · City of Hope Medical Center · Sangamo Therapeutics

Trials 1 · a red edge is where a trial was stopped

20162017201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02500849 Mar 2016 → Aug 2026 overdue HIV infectious disease City of Hope Medical Center Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as SB-728mR-HSPC ClinicalTrials.gov intervention name — accepted as the source's own label NCT02500849
Action Inhibit “a strategy to disrupt CCR5 genomic sequences in HSPC using zinc finger nucleases was developed” PMID 27900346 Nov 2016
Modality Cell therapy “before being infused with the genetically modified cells” NCT02500849
Target CCR5 “a strategy to disrupt CCR5 genomic sequences in HSPC using zinc finger nucleases was developed” PMID 27900346 Nov 2016