Drugs / SB-728mR-HSPC
last change Nov 2016 re-read 9 days ago

SB-728mR-HSPC

Cell therapy targets CCR5 via inhibition

Developed for
HIV infectious disease
Investigated by
California Institute for Regenerative Medicine (CIRM) · City of Hope Medical Center · Sangamo Therapeutics

Trials 1

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02500849 Mar 2016 → Jul 2027 expected HIV infectious disease City of Hope Medical Center Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as SB-728mR-HSPC ClinicalTrials.gov intervention name — accepted as the source's own label NCT02500849 ↗
Action Inhibit “a strategy to disrupt CCR5 genomic sequences in HSPC using zinc finger nucleases was developed” PMID 27900346 ↗ Nov 2016
Modality Cell therapy “before being infused with the genetically modified cells” NCT02500849 ↗
Target CCR5 “a strategy to disrupt CCR5 genomic sequences in HSPC using zinc finger nucleases was developed” PMID 27900346 ↗ Nov 2016