Naphazoline

also known as Albalon · Antistin-privine · Gppe nsl soln · Nafazair · Nafazolin · Nafazolina · Naphaz hcl · Naphazoline hcl · +10 more

Small molecule

Developed for: conjunctivitis · eye allergy · nasal cavity disorder
Investigated by: Bausch & Lomb Incorporated · Allergan · EMS · Hom, Milton M., OD, FAAO · Laboratorios Sophia S.A de C.V.

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Approved	US (FDA)	VASOCON	—	1971-06-07	fda.gov ↗

Trials 5 · a red edge is where a trial was stopped

today

US approved 1971

NCT05470868 · Ph 1 NCT02601235 · Ph 3 NCT01390961 · Ph 4 NCT00770133 · Ph 3 NCT00769886 · Ph 3

19701971197219731974197519761977197819791980198119821983198419851986198719881989199019911992199319941995199619971998199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 11 trial
Phase 1	NCT05470868	Feb → May 2023	ocular hyperemia	Laboratorios Sophia S.A de C.V.	Completed	No outcome recorded
Phase 33 trials
Phase 3	NCT02601235	Jan → Aug 2018	nasal cavity disorder	EMS	Completed	No outcome recorded
Phase 3	NCT00770133	Feb → Apr 2010	conjunctivitis	Bausch & Lomb Incorporated	Completed	No outcome recorded
Phase 3	NCT00769886	Oct → Dec 2008	conjunctivitis	Bausch & Lomb Incorporated	Completed	No outcome recorded
Phase 41 trial
Phase 4	NCT01390961	Aug → Dec 2011	eye allergy	Hom, Milton M., OD, FAAO	Unknown	No outcome recorded

Also used as a comparator or background therapy in 1 trial

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 1	NCT03324113 Background	Oct 2017 → Nov 2022	cancer	Sanofi	Completed	No outcome recorded

Evidence & citations 21 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

Field	Value	Cited text
Known as	naphazoline	ClinicalTrials.gov intervention name — accepted as the source's own label NCT01390961 ↗ 4 NCT00769886 ↗ NCT05470868 ↗ NCT00770133 ↗ NCT03324113 ↗
Known as	Albalon	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Antistin-privine	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Gppe nsl soln	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Nafazair	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Nafazolin	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Nafazolina	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Naphaz hcl	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Naphazoline hcl	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Naphazoline Hydrochloride	“Naphazoline Hydrochloride” NCT02601235 ↗
Known as	Naphazoline hydrochloride component of naphcon-a	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Naphazoline hydrochloride component of opcon-a	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Naphazoline hydrochloride component of vasocon-a	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Naphazoline hydrochloride component of visine	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Naphazoline hydrochloride component of visine-a	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Naphcon forte	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	NSC-35711	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Opcon	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Known as	Vasocon	ChEMBL registry synonym — accepted as the source's own label CHEMBL761 ↗
Modality	Small molecule	— CHEMBL761 ↗
Route	Other	“Naphazoline ophthalmic solution administered in either the right eye, left eye or both eyes at visit 3 and visit 4.” NCT00770133 ↗