Drugs / Malathion
last change Feb 2018 re-read 2 minutes ago

Malathion

also known as 8059HC · Cythion · Derbac-m · ENT 17,034 · MALG · NSC-6524 · Organoderm · Ovide · +4 more

Small molecule

Developed for
Pediculus humanus capitis infestation · lice infestation
Investigated by
Sun Pharmaceutical Industries, Inc.

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) OVIDE 1982-08-02 fda.gov

Trials 5 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00927407 Jul → Aug 2009 Pediculus humanus capitis infestation Sun Pharmaceutical Industries, Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00291057 Feb → Oct 2006 lice infestation Sun Pharmaceutical Industries, Inc. Terminated No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT00752973 Sep 2008 → Dec 2011 Pediculus humanus capitis infestation Sun Pharmaceutical Industries, Inc. Completed No outcome recorded
Phase 32 trials
Phase 3 NCT00927472 Aug 2009 → May 2010 Pediculus humanus capitis infestation Sun Pharmaceutical Industries, Inc. Completed No outcome recorded
Phase 3 NCT00963508 Aug 2009 → Mar 2010 lice infestation Sun Pharmaceutical Industries, Inc. Completed No outcome recorded
Also used as a comparator or background therapy in 4 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT02213055 Comparator May 2009 → Aug 2014 Pediculus humanus capitis infestation Hackensack Meridian Health Completed No outcome recorded
Phase 33 trials
Phase 3 NCT03236168 Background Aug → Dec 2017 Pediculus humanus capitis infestation, scabies London School of Hygiene and Tropical Medicine Completed No outcome recorded
Phase 3 NCT00244439 Comparator Dec 2005 → Oct 2006 Pediculus humanus capitis infestation Sun Pharmaceutical Industries, Inc. Completed No outcome recorded
Phase 3 NCT00819520 Comparator Feb → Sep 2004 lice infestation Johnson & Johnson Consumer and Personal Products Worldwide Completed No outcome recorded

Evidence & citations 15 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as malathion “a novel formulation of malathion 0.5% was evaluated in patients 2 years of age and older” NCT00291057
8

malathion (0.5%)” NCT02213055

NCT00244439

NCT00819520

NCT00752973

NCT00963508

NCT00927407

NCT00927472

NCT03236168

Known as 8059HC ChEMBL registry synonym — accepted as the source's own label CHEMBL1200468
Known as Cythion ChEMBL registry synonym — accepted as the source's own label CHEMBL1200468
Known as Derbac-m ChEMBL registry synonym — accepted as the source's own label CHEMBL1200468
Known as ENT 17,034 ChEMBL registry synonym — accepted as the source's own label CHEMBL1200468
Known as MALG MALG (malathion) Treatment” NCT00752973
Known as NSC-6524 ChEMBL registry synonym — accepted as the source's own label CHEMBL1200468
Known as Organoderm ChEMBL registry synonym — accepted as the source's own label CHEMBL1200468
Known as Ovide Ovide (malathion) lotion 0.05%” NCT00244439
Known as Ovide Lotion “0.5% malathion gel versus Ovide Lotion (0.5% malathion) or Nix Crème Rinse (1% permethrin) used as labeled, for the treatment of head lice.” PMID 17845167 Jul 2007
Known as Prioderm ChEMBL registry synonym — accepted as the source's own label CHEMBL1200468
Known as Quellada-m ChEMBL registry synonym — accepted as the source's own label CHEMBL1200468
Known as Suleo-m ChEMBL registry synonym — accepted as the source's own label CHEMBL1200468
Modality Small molecule CHEMBL1200468
Route Topical “Two single applications of malathion 0.5% lotion (Days 1 and 8)” NCT00819520