Drugs / IL13Ra2-specific CAR Tcm cells
last change Jun 2026 re-read 3 minutes ago

IL13Ra2-specific CAR Tcm cells

Cell therapy targets IL13RA2 via depletion

Developed for
glioblastoma · grade II glioma · grade III glioma
Investigated by
City of Hope Medical Center · Food and Drug Administration (FDA) · National Cancer Institute (NCI)

Trials 1

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02208362 May 2015 → Feb 2021 overdue glioblastoma, grade II glioma, grade III glioma City of Hope Medical Center Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as IL13Ra2-specific CAR Tcm cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT02208362 ↗
Action Deplete “a modified gene is placed into them in the laboratory and this may help them recognize and kill glioma cells.” NCT02208362 ↗
Modality Cell therapy “CAR-T therapy is an emerging strategy” PMID 38454126 ↗ Mar 2024
Route Other “directly into the tumor (intratumoral)” NCT02208362 ↗
Target IL13RA2 “CAR-engineered T cells targeting the tumor-associated antigen interleukin-13 receptor alpha 2 (IL13Rα2).” PMID 28029927 ↗ Dec 2016