Drugs / CAFELKIBART

Trials 10

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/25 trials
Phase 1/2 NCT06821503 Apr 2025 → Dec 2027 expected malignant pancreatic neoplasm Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT06825494 Apr 2025 → Mar 2026 overdue neoplasm Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT05518045 Aug 2022 → Oct 2026 expected neoplastic disease or syndrome LaNova Medicines Limited Active not recruiting No outcome recorded
Phase 1/2 NCT05255484 May 2022 → Oct 2023 neoplasm LaNova Medicines Limited Terminated No outcome recorded
Phase 1/2 NCT05199753 Mar 2022 → Dec 2024 neoplasm LaNova Medicines Limited Completed No outcome recorded
Phase 24 trials
Phase 2 NCT06873854 Mar 2025 → Jan 2028 expected neoplastic disease or syndrome LaNova Medicines Limited Not yet recruiting No outcome recorded
Phase 2 NCT06620822 Sep 2024 → Sep 2026 overdue non-small cell lung carcinoma Shanghai Pulmonary Hospital, Shanghai, China Not yet recruiting No outcome recorded
Phase 2 NCT06387628 Jul 2024 → Apr 2026 overdue triple-negative breast carcinoma Fudan University Recruiting No outcome recorded
Phase 2 NCT06479759 Jan 2024 → Jun 2025 non-small cell lung carcinoma Shanghai Pulmonary Hospital, Shanghai, China Unknown No outcome recorded
Phase 31 trial
Phase 3 NCT07362186 Apr 2026 → Aug 2028 expected gastric adenocarcinoma LaNova Medicines Limited Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2025-06-04 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Results 2国、22城、500+专家!“全球肿瘤进展巅峰对话”中美连线直播 谢承润:国产创新药已处国际前沿 冀“中国方案”成为“世界方案” cttq.com ↗
联合PD-1治疗胰腺癌的研究入选了本次大会的口头报告,联合疗法在二线胰腺癌患者中客观缓解率20.3%,中位OS达到10.02个月,显著优于现有治疗方案。

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as CAFELKIBART ChEMBL registry synonym — accepted as the source's own label CHEMBL6068098 ↗
Known as LM-108 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05518045 ↗
9

NCT06387628 ↗

NCT06825494 ↗

NCT06873854 ↗

NCT07362186 ↗

NCT06821503 ↗

NCT06479759 ↗

NCT05255484 ↗

NCT06620822 ↗

NCT05199753 ↗

Known as LM-108 injection “LM-108 injection is a monoclonal antibody that selectively clears regulatory T cells that infiltrate tumor sites.” NCT06825494 ↗
Action Deplete “specifically removing tumor-infiltrating regulatory T cells (Treg)” NCT06620822 ↗
Modality Monoclonal antibody “Anti-CCR8 Monoclonal Antibody” NCT05518045 ↗
Route Intravenous “Administered intravenously” NCT05199753 ↗
Target CCR8 “Anti-CCR8 Monoclonal Antibody” NCT05518045 ↗