Drugs / Otamixaban
last change May 2013 re-read 9 days ago

Otamixaban

also known as XRP0673 · FXV-673 · RPR-130673

Small molecule targets F10 via inhibition

Developed for
acute coronary syndrome · coronary artery disorder
Investigated by
Sanofi

Trials 5

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT01126086 May 2010 → Apr 2011 — Sanofi Completed No outcome recorded
Phase 1 NCT01120314 Apr 2010 → Jul 2011 impaired renal function disease Sanofi Completed No outcome recorded
Phase 22 trials · 1 missed
Phase 2 NCT00317395 Jun 2006 → Oct 2008 coronary artery disorder Sanofi Completed Missed primary
Phase 2 NCT00133731 Sep 2004 → Oct 2005 — Sanofi Completed No outcome recorded
Phase 31 trial · 1 missed
Phase 3 NCT01076764 Apr 2010 → May 2013 acute coronary syndrome Sanofi Completed Missed primary

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Otamixaban ClinicalTrials.gov intervention name — accepted as the source's own label NCT00133731 ↗
4

NCT01120314 ↗

NCT00317395 ↗

NCT01076764 ↗

NCT01126086 ↗

Known as FXV-673 ChEMBL registry synonym — accepted as the source's own label CHEMBL46618 ↗
Known as RPR-130673 ChEMBL registry synonym — accepted as the source's own label CHEMBL46618 ↗
Known as XRP0673 “Otamixaban (XRP0673)” NCT00133731 ↗
2

“OTAMIXABAN (XRP0673)” NCT01120314 ↗

“Otamixaban (XRP0673)” NCT00317395 ↗

Action Inhibit “Factor Xa Inhibitor Otamixaban” NCT00133731 ↗
1

“Coagulation factor X inhibitor” CHEMBL46618 ↗

Modality Small molecule — CHEMBL46618 ↗
Route Intravenous “intravenous regimens of Factor Xa Inhibitor Otamixaban” NCT00133731 ↗
Target F10 “Coagulation factor X inhibitor” CHEMBL46618 ↗