Drugs / Tritanrix-HepB
last change Jan 2014 re-read 2 minutes ago

Tritanrix-HepB

also known as DTPw-HBV · TritanrixTM-HepB

Vaccine

Developed for
diphtheria · hepatitis B virus infection · tetanus · haemophilus infectious disease · pertussis
Investigated by
GlaxoSmithKline · Merck Sharp & Dohme LLC

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Withdrawn EU (EMA) Tritanrix HepB 2014-01-01 europa.eu
Approved EU (EMA) Tritanrix HepB 1996-07-19 europa.eu

Trials 5 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT00291967 Nov 2002 → ? diphtheria, haemophilus infectious disease, hepatitis B virus infection, meningococcal infection +2 GlaxoSmithKline Completed No outcome recorded
Phase 34 trials
Phase 3 NCT01003431 Dec 2009 → Aug 2010 Rotavirus infection, diphtheria, pertussis, tetanus Merck Sharp & Dohme LLC Withdrawn No outcome recorded
Phase 3 NCT00317109 Apr 2006 → May 2007 meningococcal infection GlaxoSmithKline Completed No outcome recorded
Phase 3 NCT00197275 Feb → Nov 2006 diphtheria, haemophilus infectious disease, hepatitis B virus infection, tetanus GlaxoSmithKline Completed No outcome recorded
Phase 3 NCT00158756 Sep 2005 → Nov 2006 hepatitis B virus infection GlaxoSmithKline Completed No outcome recorded
Also used as a comparator or background therapy in 7 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT01061541 Comparator Aug 2003 → Jan 2004 haemophilus infectious disease GlaxoSmithKline Completed No outcome recorded
Phase 36 trials
Phase 3 NCT00814710 Comparator Mar → Nov 2009 pneumococcal infection GlaxoSmithKline Completed No outcome recorded
Phase 3 NCT00547248 Background Oct 2007 → May 2008 streptococcal infection GlaxoSmithKline Completed No outcome recorded
Phase 3 NCT00344318 Background Aug 2006 → Apr 2007 streptococcal infection GlaxoSmithKline Completed No outcome recorded
Phase 3 NCT00291343 Background Feb 2006 → Mar 2007 meningococcal infection GlaxoSmithKline Completed No outcome recorded
Phase 3 NCT00317187 Background Jun 2004 → Jan 2005 diphtheria, haemophilus infectious disease, hepatitis B virus infection, tetanus GlaxoSmithKline Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 12 sources stand behind the page.

FieldValueCited text
Known as Tritanrix- HepB “[Intervention name: RotaTeq™ administered concomitantly with Tritanrix™ HepB (DTwP)] Three 2.0 mL oral doses of RotaTeq™ and three 0.5 mL intramuscular injections of Tritanrix™ HepB” NCT01003431
10

NCT00291343

NCT01061541

NCT00197275

NCT00344318

NCT00547248

NCT00317109

NCT00317135

NCT00317187

NCT00814710

NCT00158756

Known as DTPw-HBV ClinicalTrials.gov intervention name — accepted as the source's own label NCT00291967
Known as TritanrixTM-HepB “Subjects received HiberixTM intramuscularly in the right thigh co-administered with TritanrixTM-HepB intramuscularly in the left thigh at 6-10-14 weeks of age (=study month 0, 1, 2)” NCT00814710
Modality Vaccine “GSK Biologicals' combined diphtheria-tetanus-whole cell Bordetella pertussis -hepatitis B vaccine.” NCT00158756
Route Intramuscular intramuscularly into the right anterolateral thigh” NCT00158756