Drugs / BY101298
last change Dec 2025 re-read 2 minutes ago

BY101298

also known as AMO959 · BY1298

Small molecule

Developed for
cancer · castration-resistant prostate carcinoma
Investigated by
Chengdu Baiyu Pharmaceutical Co., Ltd. · Novartis Pharmaceuticals

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06462716 Apr 2023 → Dec 2024 cancer Chengdu Baiyu Pharmaceutical Co., Ltd. Unknown No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT07226986 Dec 2025 → Jul 2028 expected castration-resistant prostate carcinoma Novartis Pharmaceuticals Recruiting No outcome recorded
Phase 1/2 NCT06524804 May → Oct 2024 cancer Chengdu Baiyu Pharmaceutical Co., Ltd. Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as BY101298 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06462716
1

NCT06524804

Known as AMO959 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07226986
Known as BY1298 “Subjects will receive a starting dose of 50 milligram (mg) of BY1298 as Capsule orally once daily, ascending to 100, 200, 300 and 400 mg.” NCT06462716
Action Inhibit “An oral DNA-PK Inhibitor” NCT06462716
Modality Small molecule “BY101298 is an innovative DNA-dependent protein kinases (DNA-PK) highly selective small molecule inhibitor.” NCT06462716
Route Oral “Capsule orally once daily” NCT06462716