Drugs / double-mutant LT
last change Jun 2012 re-read 3 minutes ago

double-mutant LT

also known as dmLT · LT(R192G/L211A)

Vaccine

Developed for
gastroenteritis
Investigated by
National Institute of Allergy and Infectious Diseases (NIAID)

Trials 1

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01147445 Sep 2010 → Jun 2012 gastroenteritis National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as double-mutant LT “The rationale for using an E. coli heat labile enterotoxin (LT) (R192G/L211A) vaccine, also called double-mutant LT (dmLT), is that it is expected to be especially well...” NCT01147445 ↗
Known as dmLT ClinicalTrials.gov intervention name — accepted as the source's own label NCT01147445 ↗
Known as LT(R192G/L211A) “LT(R192G/L211A), or dmLT is a derivative of wild-type enterotoxigenic Escherichia coli heat labile enterotoxin.” NCT01147445 ↗
Modality Vaccine “new candidate vaccine (dmLT) against ETEC (E. coli infection)” NCT01147445 ↗
Route Oral “Vaccine dosage levels: 5, 25, 50, 100 micrograms as a single, oral dose.” NCT01147445 ↗