Drugs / APLAVIROC
Trials 6 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 23 trials | ||||||
| Phase 2 | NCT00104429 | Jan 2005 → Jan 2006 | HIV infectious disease | ViiV Healthcare | Terminated | No outcome recorded |
| Phase 2 | NCT00102778 | Dec 2004 → Sep 2007 | HIV infectious disease | ViiV Healthcare | Terminated | No outcome recorded |
| Phase 2 | NCT00076284 | Jan 2004 → Mar 2005 | HIV infectious disease | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
| Phase 33 trials | ||||||
| Phase 3 | NCT00197145 | Jul 2005 → Sep 2007 | HIV infectious disease | ViiV Healthcare | Terminated | No outcome recorded |
| Phase 3 | NCT00297076 | Jul 2005 → Oct 2007 | HIV infectious disease | GlaxoSmithKline | Terminated | No outcome recorded |
| Phase 3 | NCT00197197 | Jul → Oct 2005 | HIV infectious disease | GlaxoSmithKline | Terminated | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 3 | NCT00123890 Background | Jun → Oct 2005 | HIV infectious disease | GlaxoSmithKline | Terminated | No outcome recorded |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | APLAVIROC | ChEMBL registry synonym — accepted as the source's own label CHEMBL1255794 ↗ |
| Known as | AK-602 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1255794 ↗ |
| Known as | Aplaviroc hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1255794 ↗ |
| Known as | APLAVIROC HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1255794 ↗ |
| Known as | GSK-873140 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1255794 ↗ |
| Known as | GW-873140A | ChEMBL registry synonym — accepted as the source's own label CHEMBL1255794 ↗ |
| Known as | GW873140 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00197197 ↗ |
| Action | Inhibit | “GW873140 is intended to block the CCR5 receptor so that HIV-1 cannot enter the cell.” NCT00076284 ↗ |
| Modality | Small molecule | — CHEMBL1255794 ↗ |
| Route | Oral | “following oral dosing” NCT00076284 ↗ |
| Target | CCR5 | “block the CCR5 receptor” NCT00076284 ↗ |