Drugs / Efepoetin Alfa
last change Mar 2025 re-read 2 minutes ago

Efepoetin Alfa

also known as Efepoetina alfa · Efepoetine alfa · GX-E2 · GX-E4

Protein / enzyme biologic targets EPOR via activation

Developed for
anemia due to chronic disorder
Investigated by
Genexine, Inc. · PT Kalbe Genexine Biologics · Novotech (Australia) Pty Limited

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06490939 Oct 2024 → Mar 2025 Genexine, Inc. Completed No outcome recorded
Phase 32 trials
Phase 3 NCT06466785 Jan 2024 → Jun 2027 expected anemia due to chronic disorder Genexine, Inc. Recruiting No outcome recorded
Phase 3 NCT04155125 Jul 2020 → Mar 2022 anemia due to chronic disorder PT Kalbe Genexine Biologics Completed No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Efepoetin Alfa ClinicalTrials.gov intervention name — accepted as the source's own label NCT06466785
2

NCT04155125

NCT06490939

Known as Efepoetina alfa ChEMBL registry synonym — accepted as the source's own label CHEMBL4594471
Known as Efepoetine alfa ChEMBL registry synonym — accepted as the source's own label CHEMBL4594471
Known as GX-E2 “Efepoetin alfa (Epoetin-Fc fusion protein, GX-E2 or GX-E4,) is a novel long-acting erythropoietin-hybrid fragment crystallizable (Fc) fusion protein developed by Genexine” NCT06466785
Known as GX-E4 “This study is to objectively evaluate pharmacokinetics as well as pharmacodynamic responses after a single intravenous administration of the Efepoetin alfa, GX-E4, in healthy...” NCT06490939
Action Activate “Erythropoietin receptor agonist” CHEMBL4594471
Modality Protein / enzyme biologic “Efepoetin alfa (Epoetin-Fc fusion protein, GX-E2 or GX-E4,) is a novel long-acting erythropoietin-hybrid fragment crystallizable (Fc) fusion protein developed by Genexine” NCT06466785
Route Subcutaneous subcutaneous efepoetin alfa” NCT04155125
Target EPOR “Erythropoietin receptor agonist” CHEMBL4594471