Drugs / TAK-071
last change Feb 2023 re-read 2 minutes ago

TAK-071

Small molecule targets CHRM1 via activation

Developed for
Alzheimer disease · Parkinson disease
Investigated by
Takeda · Michael J. Fox Foundation for Parkinson's Research

Trials 3 · a red edge is where a trial was stopped

2017201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02918266 Nov 2016 → Aug 2017 Takeda Terminated No outcome recorded
Phase 1 NCT02769065 May 2016 → Jun 2017 Alzheimer disease Takeda Terminated No outcome recorded
Phase 21 trial
Phase 2 NCT04334317 Oct 2020 → Feb 2023 Parkinson disease Takeda Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as TAK-071 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02769065
2

NCT04334317

NCT02918266

Action Activate “a novel muscarinic acetylcholine receptor 1 positive allosteric modulator” NCT02918266
1

“Muscarinic acetylcholine receptor M1 positive allosteric modulator” CHEMBL4594351

Modality Small molecule CHEMBL4594351
Route Oral “TAK-071 1 mg, capsule, orally, once on Day 1 to non-Japanese healthy participants.” NCT02769065
Target CHRM1 “Muscarinic acetylcholine receptor M1 positive allosteric modulator” CHEMBL4594351