Drugs / TAK-071
last change Feb 2023 re-read 9 days ago

TAK-071

Small molecule targets CHRM1 via activation

Developed for
Alzheimer disease · Parkinson disease
Investigated by
Takeda · Michael J. Fox Foundation for Parkinson's Research

Trials 3

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02918266 Nov 2016 → Aug 2017 — Takeda Terminated No outcome recorded
Phase 1 NCT02769065 May 2016 → Jun 2017 Alzheimer disease Takeda Terminated No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT04334317 Oct 2020 → Feb 2023 Parkinson disease Takeda Completed Missed primary

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as TAK-071 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02918266 ↗
2

NCT04334317 ↗

NCT02769065 ↗

Action Activate “a novel muscarinic acetylcholine receptor 1 positive allosteric modulator” NCT02918266 ↗
1

“Muscarinic acetylcholine receptor M1 positive allosteric modulator” CHEMBL4594351 ↗

Modality Small molecule — CHEMBL4594351 ↗
Route Oral “TAK-071 1 mg, capsule, orally, once on Day 1 to non-Japanese healthy participants.” NCT02769065 ↗
Target CHRM1 “Muscarinic acetylcholine receptor M1 positive allosteric modulator” CHEMBL4594351 ↗